For vanquishing Istan and Ascalon as a monk, I took Koss, Zhed and Master. Koss was an axe warrior with "Watch Yourself!", Zhed ran as an SF ele, and Master was SS with some anti-melee (hexes and Enfeebling Blood) and some anti-caster spells (Inspiration interrupts, mainly).
Istan I found easy enough with the above set up. Two SF eles would provide more firepower but I preferred the versatility and defense of Master of Whispers' build.
As a monk, I was usually running a modified bonder bar, with heavy protection and Blessed Light.
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